Zfp830 Gene Summary [Mouse]
Predicted to enable nucleic acid binding activity and zinc ion binding activity. Involved in several processes, including mitotic DNA replication checkpoint signaling; negative regulation of apoptotic process; and preantral ovarian follicle growth. Acts upstream of or within several processes, including blastocyst growth; intestinal epithelial structure maintenance; and mitotic DNA damage checkpoint signaling. Located in nuclear speck. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; gut gland; and respiratory system. Orthologous to human ZNF830 (zinc finger protein 830). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zfp830 |
| Official Name | zinc finger protein 830 [Source:MGI Symbol;Acc:MGI:1914233] |
| Ensembl ID | ENSMUSG00000046010 |
| Bio databases IDs | |
| Aliases | zinc finger protein 830 |
| Synonyms | 2410003C20Rik, CCDC16, MGC20398, OMCG1, Zfp830, zinc finger protein 830 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zfp830 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc-finger double-stranded RNA-binding
- U1 zinc finger
- protein binding
- Zinc-finger of C2H2 type
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
phenotypes
- abnormal gait
- abnormal retina morphology
- embryonic lethality prior to tooth bud stage
- preweaning lethality complete penetrance
- abnormal cell cycle
- abnormal inner cell mass morphology
- abnormal trophectoderm morphology
- absent inner cell mass proliferation
- absent trophectoderm cell proliferation
- decreased inner cell mass proliferation
- embryonic lethality at implantation complete penetrance
- embryonic lethality before implantation complete penetrance
- failure of blastocyst to hatch from the zona pellucida
- failure of embryo implantation
- no abnormal phenotype detected
role in cell
- apoptosis
- cell cycle progression
- organization
- alternative splicing in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Zfp830 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- DNA replication involved in S phase
- RNA splicing
- RNA processing
- mRNA processing
- ovarian follicle development
- cell division
- blastocyst growth
- preantral ovarian follicle growth
- chromosome organization
- intestinal epithelial structure maintenance
- negative regulation of apoptotic process
- mitotic cell cycle DNA replication checkpoint
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear speck
- spliceosomal complex
- chromosome
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- nucleic acid binding
- zinc ion binding
- protein binding