Prr12 Gene Summary [Mouse]

Predicted to enable DNA binding activity. Predicted to be located in neuron projection; nucleus; and postsynaptic density. Is expressed in central nervous system and retina. Orthologous to human PRR12 (proline rich 12). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Prr12
Official Name
proline rich 12 [Source:MGI Symbol;Acc:MGI:2679002]
Ensembl ID
ENSMUSG00000046574
Bio databases IDs NCBI: 233210 Ensembl: ENSMUSG00000046574
Aliases proline rich 12
Synonyms 6720469B10, KIAA1205, NOC, proline rich 12, RGD1309896
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prr12 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Domain of unknown function (DUF4211)

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • neuroocular syndrome 1
  • neurodevelopmental disorder
  • hereditary disorder
  • mental retardation
  • complex microphthalmia
  • skin neoplasm
  • skin neoplasia
  • Hodgkin lymphoma
  • Hodgkin disease
  • myositis
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Prr12 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • postsynaptic density
  • neuron projection

Gene-Specific Assays for Results You Can Trust

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