Mis18bp1 Gene Summary [Mouse]
Predicted to enable DNA binding activity. Predicted to be involved in cell division. Part of CENP-A recruiting complex. Is expressed in cerebral cortex ventricular layer; midbrain ventricular layer; nephrogenic zone; olfactory cortex ventricular layer; and telencephalon ventricular layer. Orthologous to human MIS18BP1 (MIS18 binding protein 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mis18bp1 |
| Official Name | MIS18 binding protein 1 [Source:MGI Symbol;Acc:MGI:2145099] |
| Ensembl ID | ENSMUSG00000047534 |
| Bio databases IDs | |
| Aliases | MIS18 binding protein 1 |
| Synonyms | 6720403H11, C14orf106, HSA242977, KNL2, M18BP1, MIS18 binding protein 1, mKIAA1903, p243, RGD1305497 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mis18bp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SANTA (SANT Associated)
- SANT
- SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
- Myb-like DNA-binding domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mis18bp1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
Cellular Component
Where in the cell the gene product is active
- chromosome, centromeric region
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding