MIS18BP1 Gene Summary [Human]

Predicted to enable DNA binding activity. Predicted to be involved in cell division. Predicted to be located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
MIS18BP1
Official Name
MIS18 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:20190]
Ensembl ID
ENSG00000129534
Bio databases IDs NCBI: 55320 Ensembl: ENSG00000129534
Aliases MIS18 binding protein 1, kinetochore null 2 homolog (C. elegans)
Synonyms 6720403H11, C14orf106, HSA242977, KNL2, M18BP1, MIS18 binding protein 1, mKIAA1903, p243, RGD1305497
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MIS18BP1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • SANTA (SANT Associated)
  • SANT
  • SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
  • Myb-like DNA-binding domain
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • prostate cancer
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human MIS18BP1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell division

Cellular Component

Where in the cell the gene product is active
  • chromosome, centromeric region
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • DNA binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.