Ninl Gene Summary [Mouse]
Predicted to enable calcium ion binding activity. Predicted to be involved in microtubule anchoring at centrosome. Predicted to be located in cytoplasm and microtubule. Predicted to be active in centrosome. Is expressed in liver left lobe and liver right lobe. Orthologous to human NINL (ninein like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ninl |
| Official Name | ninein-like [Source:MGI Symbol;Acc:MGI:1925427] |
| Ensembl ID | ENSMUSG00000068115 |
| Bio databases IDs | |
| Aliases | ninein-like |
| Synonyms | 4930519N13Rik, Gm1004, Gm1634, mKIAA0980, ninein-like, NLP, RGD1306152 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ninl often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Alpha helical coiled-coil rod protein (HCR)
- chromosome segregation protein SMC, common bacterial type
- RecF/RecN/SMC N terminal domain
- EF-hand domain
- EF-hand domain pair
- EF hand
- Transforming acidic coiled-coil-containing protein (TACC), C-terminal
- EFh
- protein binding
- KEN box
- D-Box
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- autism
- psychosis
role in cell
- proliferation
- growth
- formation
- formation in
- reorganization
- aneuploidy
- segregation
- reorganization in
- segregation in
- multinuclearity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- aggregate
- centrosome
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ninl gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- microtubule anchoring at centrosome
Cellular Component
Where in the cell the gene product is active
- centrosome
- cytosol
- microtubule
Molecular Function
What the gene product does at the molecular level
- protein binding
- calcium ion binding