Lxn Gene Summary [Mouse]
Enables metalloendopeptidase inhibitor activity. Acts upstream of or within detection of temperature stimulus involved in sensory perception of pain. Predicted to be located in cytoplasm. Predicted to be active in extracellular space. Is expressed in cartilage; central nervous system; peripheral nervous system; and tibia. Orthologous to human LXN (latexin). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Lxn |
| Official Name | latexin [Source:MGI Symbol;Acc:MGI:107633] |
| Ensembl ID | ENSMUSG00000047557 |
| Bio databases IDs | |
| Aliases | latexin |
| Synonyms | ECI, latexin, TCI |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lxn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Latexin
- protein binding
- metalloendopeptidase inhibitor
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- obesity
- impaired glucose tolerance
- hepatic steatosis
- insulin resistance
regulates
role in cell
- differentiation
- homeostasis
- ubiquitination in
- cytostasis
- adipogenesis in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Lxn gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- inflammatory response
- detection of temperature stimulus involved in sensory perception of pain
Cellular Component
Where in the cell the gene product is active
- extracellular space
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- heparin binding
- metalloendopeptidase inhibitor activity