Fancb

Acts upstream of or within several processes, including bone marrow development; cellular response to camptothecin; and regulation of double-strand break repair via homologous recombination. Predicted to be located in chromatin. Predicted to be part of Fanconi anaemia nuclear complex. Is expressed in cerebral cortex ventricular layer and cortical plate. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group B and head and neck squamous cell carcinoma. Orthologous to human FANCB (FA complementation group B). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fancb often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Fancb gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Fancb gene, providing context for its role in the cell.