Rpl29 Gene Summary [Mouse]
Enables heparin binding activity. A structural constituent of ribosome. Acts upstream of or within cell-substrate adhesion; fibroblast proliferation; and translation. Located in cytosolic ribosome and membrane. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in several structures, including bone; eye; gonad; gut; and skin. Orthologous to human RPL29 (ribosomal protein L29). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rpl29 |
| Official Name | ribosomal protein L29 [Source:MGI Symbol;Acc:MGI:99687] |
| Ensembl ID | ENSMUSG00000048758 |
| Bio databases IDs | |
| Aliases | ribosomal protein L29 |
| Synonyms | eL29, HIP, HUMRPL29, L29, ribosomal protein L29, RPL29 3 370, RPL29P10, Rpl43 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rpl29 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ribosomal L29e protein family
- structural constituent of ribosome
- heparin binding domain
- heparin binding
- RNA binding
Pathways
Biological processes and signaling networks where the Rpl29 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- diabetes mellitus
- prostate cancer
- growth failure
regulates
- reactive oxygen species
- PAPPA
role in cell
- proliferation
- cell cycle progression
- translation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- nucleolar region
- cellular membrane
- ribosome
- Nucleus
- cytosol
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rpl29 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cytoplasmic translation
- embryo implantation
- translation
Cellular Component
Where in the cell the gene product is active
- cytosolic ribosome
- cytoplasm
- membrane
- cytosol
- cytosolic large ribosomal subunit
Molecular Function
What the gene product does at the molecular level
- RNA binding
- structural constituent of ribosome
- cadherin binding
- heparin binding