Gnpda1 Gene Summary [Mouse]
Predicted to enable glucosamine-6-phosphate deaminase activity and identical protein binding activity. Predicted to be involved in UDP-N-acetylglucosamine biosynthetic process; amino sugar catabolic process; and generation of precursor metabolites and energy. Predicted to act upstream of or within fructose 6-phosphate metabolic process; fructose biosynthetic process; and glucosamine metabolic process. Located in cytoplasm. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human GNPDA1 (glucosamine-6-phosphate deaminase 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gnpda1 |
| Official Name | glucosamine-6-phosphate deaminase 1 [Source:MGI Symbol;Acc:MGI:1347054] |
| Ensembl ID | ENSMUSG00000052102 |
| Bio databases IDs | |
| Aliases | glucosamine-6-phosphate deaminase 1 |
| Synonyms | GlcN6P deaminase, glucosamine-6-phosphate deaminase 1, GNP1, GNPDA, GNPI, GPI, HLN, oscillin |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gnpda1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SugarP_isomerase
- Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
- glucosamine-6-phosphate deaminase
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
- cytoplasmic droplets
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gnpda1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- carbohydrate metabolic process
- generation of precursor metabolites and energy
- glucosamine catabolic process
- N-acetylneuraminate catabolic process
- N-acetylglucosamine catabolic process
- single fertilization
- UDP-N-acetylglucosamine biosynthetic process
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- glucosamine-6-phosphate deaminase activity
- isomerase activity