Cdc42se2 Gene Summary [Mouse]
Predicted to enable signaling adaptor activity. Predicted to be involved in regulation of signal transduction. Predicted to be located in several cellular components, including cell projection; cytoskeleton; and phagocytic cup. Predicted to be active in plasma membrane. Orthologous to human CDC42SE2 (CDC42 small effector 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cdc42se2 |
| Official Name | CDC42 small effector 2 [Source:MGI Symbol;Acc:MGI:1919979] |
| Ensembl ID | ENSMUSG00000052298 |
| Bio databases IDs | |
| Aliases | CDC42 small effector 2 |
| Synonyms | 2810404F18Rik, CDC42 small effector 2, LOC100191012, LOC686503, RGD1563924, SPEC2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cdc42se2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CRIB
- protein binding activity, bridging
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Alzheimer disease
- Crohn disease
- atopic dermatitis
- severe acute respiratory syndrome
- idiopathic scoliosis
- inflammatory bowel disease
role in cell
- growth
- blebbing
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cdc42se2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of cell shape
- regulation of Rho protein signal transduction
- phagocytosis
- regulation of signal transduction
Cellular Component
Where in the cell the gene product is active
- cytoskeleton
- cytoplasm
- cell projection
- phagocytic cup
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- signaling adaptor activity
- small GTPase binding