Exoc6 Gene Summary [Mouse]
Acts upstream of or within erythrocyte differentiation. Predicted to be located in plasma membrane. Predicted to be part of exocyst. Is expressed in central nervous system; dorsal root ganglion; foregut; genitourinary system; and liver lobe. Orthologous to human EXOC6 (exocyst complex component 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Exoc6 |
| Official Name | exocyst complex component 6 [Source:MGI Symbol;Acc:MGI:1351611] |
| Ensembl ID | ENSMUSG00000053799 |
| Bio databases IDs | |
| Aliases | exocyst complex component 6 |
| Synonyms | 4833405E05Rik, C430002C19, EXOC6A, exocyst complex component 6, hbd, msec15, SEC15, SEC15A, SEC15L, SEC15L1, SEC15L3, Sec15p, Sec6 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Exoc6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Exocyst complex subunit Sec15-like
- protein binding
- transporter
Pathways
Biological processes and signaling networks where the Exoc6 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- coronary artery disease
- glioma
- glioma formation
- non-insulin-dependent diabetes mellitus
- age-related hearing loss
- metabolic syndrome X
- restless legs syndrome
- open-angle glaucoma
- hearing loss
regulates
- EGFR
- heavy metal
- mir-433
- tubulin
- heme
- Delta
- TF
role in cell
- migration
- proliferation
- expression in
- apoptosis
- differentiation
- synthesis in
- uptake in
- invasion by
- glycolysis in
- incorporation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cytosol
- multivesicular bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Exoc6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- membrane fission
- cytokinesis after mitosis
- vesicle docking involved in exocytosis
- Golgi to plasma membrane transport
- intracellular protein transport
- exocytosis
Cellular Component
Where in the cell the gene product is active
- growth cone
- perinuclear region of cytoplasm
- cytosol
- plasma membrane
- exocyst
Molecular Function
What the gene product does at the molecular level
- protein binding