Pld5 Gene Summary [Mouse]

Predicted to enable hydrolase activity, acting on ester bonds. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human PLD5 (phospholipase D family member 5). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Nonsense Mediated Decay
Official Symbol
Pld5
Official Name
phospholipase D family, member 5 [Source:MGI Symbol;Acc:MGI:2442056]
Ensembl ID
ENSMUSG00000055214
Bio databases IDs NCBI: 319455 Ensembl: ENSMUSG00000055214
Aliases phospholipase D family, member 5
Synonyms B230365F16Rik, GE1475254, phospholipase D family member 5, phospholipase D family, member 5, PLDC, RGD1562609
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pld5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Phospholipase D Active site motif
  • phospholipase D
  • PLD-like domain
  • Catalytic domain of phospholipase D superfamily proteins

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • dementia
  • myopia
  • coronary artery disease
  • lung squamous cell carcinoma
  • squamous cell lung cancer
  • refractive error
  • osteoarthropathy
regulated by
role in cell
  • cell death

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Pld5 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • membrane

Molecular Function

What the gene product does at the molecular level
  • catalytic activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.