Pde4dip Gene Summary [Mouse]
Predicted to enable enzyme binding activity and molecular adaptor activity. Predicted to be involved in microtubule cytoskeleton organization; protein-containing complex assembly; and regulation of organelle organization. Predicted to be located in myofibril and nucleus. Predicted to be active in Golgi apparatus and centrosome. Predicted to colocalize with cortical microtubule plus-end. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human PDE4DIP (phosphodiesterase 4D interacting protein). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pde4dip |
| Official Name | phosphodiesterase 4D interacting protein (myomegalin) [Source:MGI Symbol;Acc:MGI:1891434] |
| Ensembl ID | ENSMUSG00000038170 |
| Bio databases IDs | |
| Aliases | phosphodiesterase 4D interacting protein (myomegalin) |
| Synonyms | 4732458A06Rik, 9430063L05Rik, D130016K21Rik, D3Bwg1078e, mKIAA0454, Myomegalin, phosphodiesterase 4D interacting protein (myomegalin), Usmg4 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pde4dip often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mitotic checkpoint protein
- Olduvai domain
- chromosome segregation protein SMC, primarily archaeal type
- exonuclease SbcC
- Centrosomin N-terminal motif 1
- rad50
- Synaptonemal complex protein 1 (SCP-1)
- enzyme binding
- Zinc-finger associated domain (zf-AD)
- protein binding
- Calcium binding and coiled-coil domain (CALCOCO1) like
- chromosome segregation protein SMC, common bacterial type
- RecF/RecN/SMC N terminal domain
- RIM-binding protein of the cytomatrix active zone
- Short myomegalin-like EB1 binding proteins, N-terminal domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- centrosome
- Golgi Apparatus
- microtubules
- myofibrils