Slc38a10 Gene Summary [Mouse]
Predicted to enable L-amino acid transmembrane transporter activity. Acts upstream of or within bone development. Predicted to be located in Golgi apparatus. Predicted to be active in membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human SLC38A10 (solute carrier family 38 member 10). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slc38a10 |
| Official Name | solute carrier family 38, member 10 [Source:MGI Symbol;Acc:MGI:1919305] |
| Ensembl ID | ENSMUSG00000061306 |
| Bio databases IDs | |
| Aliases | solute carrier family 38, member 10 |
| Synonyms | 1810073N04Rik, LOC100131419, PP1744, RGD1306356, SNAT10, solute carrier family 38 member 10, solute carrier family 38, member 10 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc38a10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins
- KLF1_2_4_N
- Proline-rich protein
- Solute carrier families 5 and 6-like; solute binding domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- insomnia
- frontotemporal dementia
- osteoarthropathy
phenotypes
- abnormal bone structure
- abnormal eye morphology
- abnormal gait
- abnormal response to tactile stimuli
- abnormal retina morphology
- abnormal startle reflex
- decreased body length
- decreased bone mineral content
- decreased circulating LDL cholesterol level
- decreased circulating alkaline phosphatase level
- decreased circulating amylase level
- decreased circulating calcium level
- decreased circulating free fatty acid level
- decreased circulating magnesium level
- decreased circulating serum albumin level
- decreased circulating sodium level
- decreased circulating total protein level
- decreased circulating triglyceride level
- decreased erythrocyte cell number
- decreased grip strength
- decreased heart weight
- decreased hemoglobin content
- decreased lean body mass
- increased bone mineral content
- increased circulating HDL cholesterol level
- increased circulating aspartate transaminase level
- increased circulating glycerol level
- increased circulating iron level
- increased circulating phosphate level
- increased circulating potassium level
- increased mean corpuscular hemoglobin concentration
- increased mean corpuscular volume
- increased mean platelet volume
- lipid depletion
- lipid deposition
- short tibia
- thrombocytopenia
- abnormal bone mineralization
- abnormal circulating HDL cholesterol level
- abnormal circulating alkaline phosphatase level
- abnormal circulating iron level
- abnormal cranium morphology
- abnormal liver physiology
- abnormal maxilla morphology
- abnormal platelet volume
- decreased body weight
- decreased bone mineral density
- decreased length of long bones
- decreased total body fat amount
- fragile skeleton
- increased circulating creatinine level
- increased circulating triglyceride level
- increased energy expenditure
- increased oxygen consumption
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc38a10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- amino acid transmembrane transport
- bone development
Cellular Component
Where in the cell the gene product is active
- membrane
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- L-amino acid transmembrane transporter activity