Kcnj15 Gene Summary [Mouse]
Enables potassium channel activity. Acts upstream of or within potassium ion transport. Predicted to be located in membrane. Predicted to be part of monoatomic ion channel complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Orthologous to human KCNJ15 (potassium inwardly rectifying channel subfamily J member 15). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kcnj15 |
| Official Name | potassium inwardly-rectifying channel, subfamily J, member 15 [Source:MGI Symbol;Acc:MGI:1310000] |
| Ensembl ID | ENSMUSG00000062609 |
| Bio databases IDs | |
| Aliases | potassium inwardly-rectifying channel, subfamily J, member 15 |
| Synonyms | 4930414N08Rik, AI182284, AI267127, IRKK, KIR1.3, KIR4.2, potassium inwardly rectifying channel subfamily J member 15, potassium inwardly-rectifying channel, subfamily J, member 15 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kcnj15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- potassium channel
- inward rectifier potassium channel
- cytoplasmic domain
- Inward rectifier potassium channel C-terminal domain
- Inward rectifier potassium channel transmembrane domain
- protein binding
- ion channel
Pathways
Biological processes and signaling networks where the Kcnj15 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- rheumatoid arthritis
- acute myeloid leukemia
- peritonsillar abscess disorder
- renal clear cell adenocarcinoma
- renal clear cell cancer
regulates
- insulin
- K+
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- basolateral membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Kcnj15 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- potassium ion transport
- regulation of ion transmembrane transport
Cellular Component
Where in the cell the gene product is active
- ion channel complex
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- inward rectifier potassium channel activity