Scoc Gene Summary [Mouse]

Predicted to be involved in positive regulation of macroautophagy and regulation of protein complex stability. Predicted to be located in Golgi apparatus and nucleoplasm. Predicted to colocalize with endosome and trans-Golgi network. Is expressed in ganglia. Orthologous to human SCOC (short coiled-coil protein). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Processed Transcript
Official Symbol
Scoc
Official Name
short coiled-coil protein [Source:MGI Symbol;Acc:MGI:1927654]
Ensembl ID
ENSMUSG00000063253
Bio databases IDs NCBI: 56367 Ensembl: ENSMUSG00000063253
Aliases short coiled-coil protein
Synonyms 0610011C06Rik, 2810002J11Rik, HRIHFB2072, SCOCO, short coiled-coil protein, UNC-69
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Scoc often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Short coiled-coil protein
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Huntington disease
  • rectum cancer
  • multiple system atrophy
  • juvenile rheumatoid arthritis
regulated by
  • megakaryocytes
  • GRN
  • UCHL3
  • ACHE
  • brefeldin A
  • KLF3
  • HK cells
  • colistin
  • gentamicin
  • metronidazole
role in cell
  • macroautophagy in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • perinuclear region
  • Plasma Membrane
  • endosomes
  • Golgi Apparatus
  • cytosol
  • trans Golgi network
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Scoc gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of macroautophagy

Cellular Component

Where in the cell the gene product is active
  • trans-Golgi network
  • endosome
  • cytosol
  • Golgi apparatus
  • Golgi membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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