Cnfn Gene Summary [Mouse]
Predicted to be involved in keratinization. Predicted to be located in cytoplasm. Predicted to be active in cornified envelope. Is expressed in external naris. Orthologous to human CNFN (cornifelin). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cnfn |
| Official Name | cornifelin [Source:MGI Symbol;Acc:MGI:1919633] |
| Ensembl ID | ENSMUSG00000063651 |
| Bio databases IDs | |
| Aliases | cornifelin |
| Synonyms | 2210418J09Rik, cornifelin, PLAC8L2, RGD1563577 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cnfn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- PLAC8 family
- zDHHC ankyrin repeat binding domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- lung adenocarcinoma
- lung adenocarcinoma formation
- squamous-cell carcinoma
- squamous cell cancer
- keratocystic odontogenic tumor
- keratocystic odontogenic tumors
- papilloma
- papillomatosis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cornified envelope
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cnfn gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- keratinization
Cellular Component
Where in the cell the gene product is active
- cornified envelope
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding