Cdc26 Gene Summary [Mouse]
Predicted to be involved in anaphase-promoting complex-dependent catabolic process; protein polyubiquitination; and regulation of mitotic cell cycle. Predicted to be part of anaphase-promoting complex. Is expressed in cerebral cortex and pancreas epithelium. Orthologous to human CDC26 (cell division cycle 26). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Cdc26 |
| Official Name | cell division cycle 26 [Source:MGI Symbol;Acc:MGI:1913690] |
| Ensembl ID | ENSMUSG00000066149 |
| Bio databases IDs | |
| Aliases | cell division cycle 26 |
| Synonyms | 2010012C09Rik, ANAPC12, APC12, BWK-2, C9orf17, cell division cycle 26 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cdc26 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Anaphase-promoting complex APC subunit CDC26
- protein binding
Pathways
Biological processes and signaling networks where the Cdc26 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cdc26 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- regulation of meiotic cell cycle
- protein K11-linked ubiquitination
- protein K48-linked ubiquitination
- anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
- regulation of mitotic cell cycle
Cellular Component
Where in the cell the gene product is active
- anaphase-promoting complex
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding