Gprin1 Gene Summary [Mouse]
Enables phosphoprotein binding activity. Acts upstream of or within neuron projection development. Located in plasma membrane. Is expressed in several structures, including axial skeleton; bone; central nervous system; peripheral nervous system ganglion; and sensory organ. Orthologous to human GPRIN1 (G protein regulated inducer of neurite outgrowth 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gprin1 |
| Official Name | G protein-regulated inducer of neurite outgrowth 1 [Source:MGI Symbol;Acc:MGI:1349455] |
| Ensembl ID | ENSMUSG00000069227 |
| Bio databases IDs | |
| Aliases | G protein-regulated inducer of neurite outgrowth 1 |
| Synonyms | G protein-regulated inducer of neurite outgrowth 1, GRIN1, KIAA1893, Z16 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gprin1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- phosphoprotein binding
- G protein-regulated inducer of neurite outgrowth C-terminus
- protein binding
- GalphaO binding domain
Pathways
Biological processes and signaling networks where the Gprin1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- lung adenocarcinoma formation
- organismal death
- lung adenocarcinoma
role in cell
- activation in
- outgrowth
- formation
- morphology
- morphogenesis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- membrane fraction
- cellular membrane
- synaptic vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gprin1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- neuron projection development
Cellular Component
Where in the cell the gene product is active
- growth cone
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- phosphoprotein binding