Pcnp Gene Summary [Mouse]
Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein ubiquitination. Predicted to be located in nuclear body. Predicted to be active in nucleus. Is expressed in embryo. Orthologous to human PCNP (PEST proteolytic signal containing nuclear protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pcnp |
| Official Name | PEST proteolytic signal containing nuclear protein [Source:MGI Symbol;Acc:MGI:1923552] |
| Ensembl ID | ENSMUSG00000071533 |
| Bio databases IDs | |
| Aliases | PEST proteolytic signal containing nuclear protein |
| Synonyms | 1110018D06RIK, Ab2-416, PEST proteolytic signal containing nuclear protein |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pcnp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- PEST, proteolytic signal-containing nuclear protein family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nuclear bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pcnp gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteasomal ubiquitin-dependent protein catabolic process
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear body
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding