PCNP Gene Summary [Human]
Involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein ubiquitination. Located in nuclear body. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | PCNP |
| Official Name | PEST proteolytic signal containing nuclear protein [Source:HGNC Symbol;Acc:HGNC:30023] |
| Ensembl ID | ENSG00000081154 |
| Bio databases IDs | |
| Aliases | PEST proteolytic signal containing nuclear protein |
| Synonyms | 1110018D06RIK, Ab2-416, PEST proteolytic signal containing nuclear protein |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PCNP often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- PEST, proteolytic signal-containing nuclear protein family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nuclear bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PCNP gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteasomal ubiquitin-dependent protein catabolic process
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear body
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding