Defb26 Gene Summary [Mouse]

Orthologous to human DEFB125 (defensin beta 125). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Defb26
Official Name
defensin beta 26 [Source:MGI Symbol;Acc:MGI:3643488]
Ensembl ID
ENSMUSG00000074680
Bio databases IDs NCBI: 654457 Ensembl: ENSMUSG00000074680
Aliases defensin beta 26
Synonyms DEFB-25, Defb26, defensin beta 125, defensin beta 26, defensin β 125, defensin β 26, EG654457, LOC100911232
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Defb26 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Beta defensin
  • beta-defensin domain found in gallinacin-11 (Gal-11) and gallinacin-13 (Gal-13)

Pathways

Biological processes and signaling networks where the Defb26 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Defb26 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • defense response to Gram-negative bacterium
  • innate immune response

Cellular Component

Where in the cell the gene product is active
  • extracellular region

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.