Hspa12b Gene Summary [Mouse]

Predicted to enable ATP binding activity. Acts upstream of or within angiogenesis and endothelial cell migration. Is expressed in nervous system; retina; smooth muscle tissue; and stomach. Orthologous to human HSPA12B (heat shock protein family A (Hsp70) member 12B). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Hspa12b
Official Name
heat shock protein 12B [Source:MGI Symbol;Acc:MGI:1919880]
Ensembl ID
ENSMUSG00000074793
Bio databases IDs NCBI: 72630 Ensembl: ENSMUSG00000074793
Aliases heat shock protein 12B
Synonyms 2700081N06Rik, C20orf60, heat shock protein 12B, heat shock protein family A (Hsp70) member 12B
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Hspa12b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • ASKHA_ATPase-like

Pathways

Biological processes and signaling networks where the Hspa12b gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • spontaneous preterm birth
  • idiopathic inflammatory myopathy
  • idiopathic pulmonary fibrosis
regulated by
regulates
role in cell
  • migration

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Hspa12b gene, providing context for its role in the cell.

Molecular Function

What the gene product does at the molecular level
  • ATP binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.