HSPA12B Gene Summary [Human]
The protein encoded by this gene contains an atypical heat shock protein 70 (Hsp70) ATPase domain and is therefore a distant member of the mammalian Hsp70 family. This gene may be involved in susceptibility to atherosclerosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Details
| Type | Protein Coding |
| Official Symbol | HSPA12B |
| Official Name | heat shock protein family A (Hsp70) member 12B [Source:HGNC Symbol;Acc:HGNC:16193] |
| Ensembl ID | ENSG00000132622 |
| Bio databases IDs | |
| Aliases | heat shock protein family A (Hsp70) member 12B |
| Synonyms | 2700081N06Rik, C20orf60, heat shock protein 12B, heat shock protein family A (Hsp70) member 12B |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human HSPA12B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- ASKHA_ATPase-like
Pathways
Biological processes and signaling networks where the HSPA12B gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human HSPA12B gene, providing context for its role in the cell.
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein binding