B3galt5 Gene Summary [Mouse]

Predicted to enable N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity. Acts upstream of or within response to bacterium. Predicted to be active in Golgi membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and visual system. Orthologous to human B3GALT5 (beta-1,3-galactosyltransferase 5). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
B3galt5
Official Name
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 [Source:MGI Symbol;Acc:MGI:2136878]
Ensembl ID
ENSMUSG00000074892
Bio databases IDs NCBI: 93961 Ensembl: ENSMUSG00000074892
Aliases UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
Synonyms 1190002B21Rik, B3GalT-V, B3GalTx, B3T5, Beta-1,3-galactosyltransferase 5, beta-1,3-GalTase 5, beta3Gal-T5, beta-3-Gx-T5, GLCT5, LOC105372805, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5, UDP-Gal:betaGlcNAc β 1,3-galactosyltransferase, polypeptide 5, β-1,3-galactosyltransferase 5, β-1,3-GalTase 5, β-3-Gx-T5
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse B3galt5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase
  • galactosyltransferase
  • enzyme
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • gout
  • organismal death
  • flu
  • COVID-19
  • diabetic nephropathy
  • acute myeloid leukemia
  • alcoholism
  • suicide attempt
regulated by
  • prostaglandin E2
  • tretinoin
  • Caco2 cells
  • MECP2
  • HMGA1
  • HTT
  • HNF1B
  • levodopa
  • 2-amino-5-phosphonovaleric acid
  • decitabine
regulates
  • sialyl Lewis a
  • galactosyl-1-3-globotetraosylceramide
  • RIPK1
  • PTK2
  • lewis a
  • oligosaccharide
role in cell
  • synthesis in
  • apoptosis
  • interaction in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • perinuclear region
  • Golgi membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse B3galt5 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • response to bacterium
  • protein O-linked glycosylation
  • lipid metabolic process
  • protein glycosylation
  • oligosaccharide biosynthetic process

Cellular Component

Where in the cell the gene product is active
  • Golgi membrane
  • Golgi apparatus
  • endoplasmic reticulum

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity

Gene-Specific Assays for Results You Can Trust

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