Rpl39 Gene Summary [Mouse]
A structural constituent of ribosome. Involved in cytoplasmic translation. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is expressed in 1-cell stage embryo; 2-cell stage embryo; and 4-cell stage embryo. Orthologous to human RPL39 (ribosomal protein L39). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rpl39 |
| Official Name | ribosomal protein L39 [Source:MGI Symbol;Acc:MGI:1914498] |
| Ensembl ID | ENSMUSG00000079641 |
| Bio databases IDs | |
| Aliases | ribosomal protein L39 |
| Synonyms | 2810465O16Rik, eL39, L39, ribosomal protein L39, RPL39 23 1806, RPL39P42 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rpl39 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ribosomal L39 protein
- structural constituent of ribosome
- protein binding
- RNA binding
Pathways
Biological processes and signaling networks where the Rpl39 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- early-onset preeclampsia
- metabolic syndrome X
role in cell
- quantity
- expression in
- proliferation
- invasion by
- morphology
- number
- migration
- cisplatin resistance
- translation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Extracellular Space
- ribosome
- Mitochondria
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rpl39 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- innate immune response in mucosa
- cytoplasmic translation
- antibacterial humoral response
- defense response to Gram-positive bacterium
- translation
Cellular Component
Where in the cell the gene product is active
- extracellular space
- cytosolic ribosome
- cytosol
- cytosolic large ribosomal subunit
Molecular Function
What the gene product does at the molecular level
- RNA binding
- structural constituent of ribosome