Uckl1 Gene Summary [Mouse]
Predicted to enable uridine kinase activity. Predicted to be involved in CMP biosynthetic process and UMP salvage. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is expressed in central nervous system; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human UCKL1 (uridine-cytidine kinase 1 like 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Uckl1 |
| Official Name | uridine-cytidine kinase 1-like 1 [Source:MGI Symbol;Acc:MGI:1915806] |
| Ensembl ID | ENSMUSG00000089917 |
| Bio databases IDs | |
| Aliases | uridine-cytidine kinase 1-like 1 |
| Synonyms | 1110007H10RIK, FLJ20517, RGD1565465, UCK1L, uridine-cytidine kinase 1-like 1, URKL1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Uckl1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- uridine kinase
- NK
- uracil phosphoribosyltransferase
- Phosphoribosyl transferase (PRT)-type I domain
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Uckl1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- pyrimidine nucleoside salvage
- CTP salvage
- CMP biosynthetic process
- UMP salvage
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein binding
- uridine kinase activity
- cytidine kinase activity