Col6a5 Gene Summary [Mouse]
Predicted to be an extracellular matrix structural constituent conferring tensile strength. Predicted to be involved in extracellular matrix organization. Located in extracellular matrix. Is expressed in several structures, including diaphragm; genitourinary system; gut; musculoskeletal system; and spleen. Orthologous to human COL6A5 (collagen type VI alpha 5 chain). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Col6a5 |
| Official Name | collagen, type VI, alpha 5 [Source:MGI Symbol;Acc:MGI:3648134] |
| Ensembl ID | ENSMUSG00000091345 |
| Bio databases IDs | |
| Aliases | collagen, type VI, alpha 5 |
| Synonyms | COL29A1, collagen, type VI, alpha 5, collagen type VI alpha 5 chain, collagen, type VI, α 5, collagen type VI α 5 chain, EG665033, Gm7455, LOC100503293, RGD1307220, RGD1565804, VWA4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Col6a5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- extracellular matrix structural constituent conferring tensile strength
- von Willebrand factor (vWF) type A domain
- vWFA
- Collagen triple helix repeat (20 copies)
- von Willebrand factor type A domain
- Proline-rich protein
- protein binding
Pathways
Biological processes and signaling networks where the Col6a5 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- extracellular matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Col6a5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell adhesion
Cellular Component
Where in the cell the gene product is active
- collagen
- extracellular region
Molecular Function
What the gene product does at the molecular level
- protein binding
- extracellular matrix structural constituent conferring tensile strength