Col6a5 Gene Summary [Rat]

Predicted to be involved in extracellular matrix organization. Predicted to be located in extracellular matrix and extracellular region. Predicted to be active in collagen-containing extracellular matrix. Orthologous to human COL6A5 (collagen type VI alpha 5 chain). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Col6a5
Official Name
collagen type VI alpha 5 chain [Source:RGD Symbol;Acc:1565804]
Ensembl ID
ENSRNOG00000010663
Bio databases IDs NCBI: 501047 Ensembl: ENSRNOG00000010663
Aliases collagen type VI alpha 5 chain
Synonyms COL29A1, collagen, type VI, alpha 5, collagen type VI alpha 5 chain, collagen, type VI, α 5, collagen type VI α 5 chain, EG665033, Gm7455, LOC100503293, RGD1307220, RGD1565804, VWA4
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Col6a5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • extracellular matrix structural constituent conferring tensile strength
  • von Willebrand factor (vWF) type A domain
  • vWFA
  • Collagen triple helix repeat (20 copies)
  • von Willebrand factor type A domain
  • Proline-rich protein
  • protein binding

Pathways

Biological processes and signaling networks where the Col6a5 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • metastasis
  • hypertension
  • chronic kidney disease
  • acute myeloid leukemia
  • diabetic nephropathy
regulated by
role in cell
  • migration
  • invasion by
  • epithelial-mesenchymal transition

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • extracellular matrix

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Col6a5 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell adhesion

Cellular Component

Where in the cell the gene product is active
  • collagen
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • extracellular matrix structural constituent conferring tensile strength

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.