Pvrig Gene Summary [Mouse]
Predicted to enable phosphatase binding activity and signaling receptor activity. Predicted to be involved in negative regulation of T cell receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to human PVRIG (PVR related immunoglobulin domain containing). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pvrig |
| Official Name | poliovirus receptor related immunoglobulin domain containing [Source:MGI Symbol;Acc:MGI:5596028] |
| Ensembl ID | ENSMUSG00000109713 |
| Bio databases IDs | |
| Aliases | poliovirus receptor related immunoglobulin domain containing |
| Synonyms | AABR07035561.2, C7orf15, CD112R, Gm36869, poliovirus receptor related immunoglobulin domain containing, PVR related immunoglobulin domain containing |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pvrig often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- signaling receptor activity
- immunoglobulin domain
- protein binding
- phosphatase binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pvrig gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of T cell receptor signaling pathway
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- phosphatase binding
- protein binding
- signaling receptor activity