St6galnac1 Gene Summary [Rat]
Predicted to enable alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity. Predicted to be involved in host-mediated regulation of intestinal microbiota composition; oligosaccharide biosynthetic process; and protein glycosylation. Predicted to be active in Golgi membrane. Orthologous to human ST6GALNAC1 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | St6galnac1 |
| Official Name | ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 [Source:RGD Symbol;Acc:1562048] |
| Ensembl ID | ENSRNOG00000000251 |
| Bio databases IDs | |
| Aliases | ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 |
| Synonyms | HSY11339, Sialyltransferase 7A, SIAT7A, ST6GALNACI, ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, ST6 N-acetylgalactosaminide α-2,6-sialyltransferase 1, STYI |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat St6galnac1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Glycosyltransferase family 29 (sialyltransferase)
- glycosyltransferase family 29
- alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- keratocystic odontogenic tumor
- keratocystic odontogenic tumors
- inflammatory bowel disease
- aortic valve calcification
- latent tuberculosis
role in cell
- expression in
- degradation in
- adhesion
- substrate adhesion
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- Golgi membrane
- Golgi stacks
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat St6galnac1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- homeostasis of number of cells in a free-living population
- protein glycosylation
- oligosaccharide biosynthetic process
Cellular Component
Where in the cell the gene product is active
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity
- protein binding
- sialyltransferase activity