Fkbpl Gene Summary [Rat]

Predicted to act upstream of or within regulation of blood vessel branching. Predicted to be located in extracellular region. Orthologous to human FKBPL (FKBP prolyl isomerase like). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Fkbpl
Official Name
FKBP prolyl isomerase like [Source:RGD Symbol;Acc:1303227]
Ensembl ID
ENSRNOG00000000432
Bio databases IDs NCBI: 406168 Ensembl: ENSRNOG00000000432
Aliases FKBP prolyl isomerase like
Synonyms DIR1, FK506 binding protein-like, FKBP prolyl isomerase like, NG7, Ppiase-X, WISP39
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fkbpl often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • TPR repeat
  • Tetratricopeptide repeats
  • protein binding
  • tetratricopeptide repeat

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • preeclampsia
  • hypothyroidism
regulated by
regulates
role in cell
  • expression in
  • binding in
  • cell death
  • migration
  • morphology
  • stabilization in
  • serine phosphorylation in
  • dephosphorylation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Extracellular Space
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Fkbpl gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • response to radiation

Cellular Component

Where in the cell the gene product is active
  • cytosol
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.