FKBPL Gene Summary [Human]
The protein encoded by this gene has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | FKBPL |
| Official Name | FKBP prolyl isomerase like [Source:HGNC Symbol;Acc:HGNC:13949] |
| Ensembl ID | ENSG00000204315 |
| Bio databases IDs | |
| Aliases | FKBP prolyl isomerase like, WAF-1/CIP1 stabilizing protein 39 |
| Synonyms | DIR1, FK506 binding protein-like, FKBP prolyl isomerase like, NG7, Ppiase-X, WISP39 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human FKBPL often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TPR repeat
- Tetratricopeptide repeats
- protein binding
- tetratricopeptide repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Extracellular Space
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human FKBPL gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to radiation
Cellular Component
Where in the cell the gene product is active
- cytosol
- extracellular region
Molecular Function
What the gene product does at the molecular level
- protein binding