Fkbpl Gene Summary [Mouse]
Acts upstream of or within regulation of blood vessel branching. Predicted to be located in extracellular region. Is expressed in several structures, including eye; gut; hemolymphoid system; male reproductive gland or organ; and nervous system. Orthologous to human FKBPL (FKBP prolyl isomerase like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fkbpl |
| Official Name | FK506 binding protein-like [Source:MGI Symbol;Acc:MGI:1932127] |
| Ensembl ID | ENSMUSG00000033739 |
| Bio databases IDs | |
| Aliases | FK506 binding protein-like |
| Synonyms | DIR1, FK506 binding protein-like, FKBP prolyl isomerase like, NG7, Ppiase-X, WISP39 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fkbpl often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TPR repeat
- Tetratricopeptide repeats
- protein binding
- tetratricopeptide repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Extracellular Space
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fkbpl gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to radiation
Cellular Component
Where in the cell the gene product is active
- cytosol
- extracellular region
Molecular Function
What the gene product does at the molecular level
- protein binding