Sult1e1 Gene Summary [Rat]
Enables estrone sulfotransferase activity. Predicted to be involved in several processes, including 3'-phosphoadenosine 5'-phosphosulfate metabolic process; estrogen catabolic process; and ethanol catabolic process. Predicted to act upstream of or within female pregnancy and sulfation. Predicted to be located in cytosol and nuclear membrane. Human ortholog(s) of this gene implicated in breast cancer and endometrial cancer. Orthologous to human SULT1E1 (sulfotransferase family 1E member 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sult1e1 |
| Official Name | sulfotransferase family 1E member 1 [Source:RGD Symbol;Acc:3776] |
| Ensembl ID | ENSRNOG00000001957 |
| Bio databases IDs | |
| Aliases | sulfotransferase family 1E member 1 |
| Synonyms | EST, EST-1, EST-2, EST-3, EST-6, Estrogen sulfotransferase, Estrogen Sulfotransferase 1, Estrogen sulphotransferase, Estrogen sulphotransferase 1, ESTSUL, rEST-6, ST1E1, St1e5, Ste, Ste1, ste2, sulfotransferase family 1E member 1, sulfotransferase family 1E, member 1, sulphotransferase family 1E member 1, sulphotransferase family 1E, member 1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Sult1e1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- sulfotransferase
- steroid sulfotransferase
- estrone sulfotransferase
- Sulfotransferase domain
- enzyme
- flavonol 3-sulfotransferase
Pathways
Biological processes and signaling networks where the Sult1e1 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- acute lung injury
- liver neoplasia
- experimental hepatitis
- hyperplasia
- placental thrombosis
- liver neoplasm
role in cell
- activation in
- size
- hypertrophy
- differentiation
- quantity
- abnormal morphology
- motility
- mobilization
- function
- infiltration by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
- nuclear envelope