Akap10 Gene Summary [Rat]
Predicted to enable protein kinase A binding activity. Predicted to be involved in protein localization. Predicted to be located in cytosol. Predicted to be part of protein-containing complex. Predicted to be active in mitochondrion and plasma membrane. Orthologous to human AKAP10 (A-kinase anchoring protein 10). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Akap10 |
| Official Name | A-kinase anchoring protein 10 [Source:RGD Symbol;Acc:1308869] |
| Ensembl ID | ENSRNOG00000002899 |
| Bio databases IDs | |
| Aliases | A-kinase anchoring protein 10 |
| Synonyms | 1500031L16Rik, A-kinase anchoring protein 10, A kinase anchor protein 10, B130049N18RIK, D-AKAP-2, PRKA10 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Akap10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Regulator of G protein signaling domain
- protein kinase A binding
- Regulator of G protein signaling (RGS) domain superfamily
- protein binding
Pathways
Biological processes and signaling networks where the Akap10 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Alzheimer disease
- breast cancer
- gastric adenocarcinoma
- bipolar disorder
- gastric epithelial cancer
- migraines
- arrhythmia
regulated by
- beta-estradiol
- Z-LLL-CHO
- GnRH analog
role in cell
- expression in
- production in
- phosphorylation in
- shortening
- disruption in
- contraction
- relaxation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
- Mitochondria
- cytosol
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Akap10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- signal transduction
- protein localization
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- cytosol
- macromolecular complex
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- protein kinase A binding