Ubxn6 Gene Summary [Rat]
Predicted to enable ATPase binding activity. Predicted to be involved in ERAD pathway; endosome to lysosome transport via multivesicular body sorting pathway; and macroautophagy. Predicted to be located in bounding membrane of organelle and cytosol. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm. Orthologous to human UBXN6 (UBX domain protein 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ubxn6 |
| Official Name | UBX domain protein 6 [Source:RGD Symbol;Acc:1590866] |
| Ensembl ID | ENSRNOG00000048509 |
| Bio databases IDs | |
| Aliases | UBX domain protein 6 |
| Synonyms | 1200008L11Rik, 2210415J11Rik, UBXD1, UBXDC2, UBX domain-containing 1, UBX domain protein 6 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ubxn6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ATPase binding
- Ubl1_cv_Nsp3_N-like
- PNGase/UBA or UBX (PUB) domain of p97 adaptor proteins
- PUB domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- pH resistant lipid raft fraction
- cellular membrane
- endosomes
- cytosol
- lysosome membrane
- endosomal membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ubxn6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- endosome to lysosome transport via multivesicular body sorting pathway
- macroautophagy
Cellular Component
Where in the cell the gene product is active
- early endosome membrane
- late endosome membrane
- nucleus
- centrosome
- endosome
- extracellular vesicular exosome
- cytoplasm
- membrane
- cytosol
- macromolecular complex
- lysosomal membrane
Molecular Function
What the gene product does at the molecular level
- protein binding