Ccne2

Enables protein kinase binding activity. Predicted to be involved in G1/S transition of mitotic cell cycle and positive regulation of G1/S transition of mitotic cell cycle. Predicted to act upstream of or within several processes, including DNA replication initiation; chromosome organization; and regulation of protein localization. Predicted to be part of cyclin E1-CDK2 complex and cyclin E2-CDK2 complex. Predicted to be active in cytoplasm; microtubule organizing center; and nucleus. Human ortholog(s) of this gene implicated in castration-resistant prostate carcinoma. Orthologous to human CCNE2 (cyclin E2). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ccne2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Ccne2 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Ccne2 gene, providing context for its role in the cell.