Pard6b Gene Summary [Rat]

Predicted to be involved in several processes, including centrosome cycle; establishment or maintenance of cell polarity; and protein-containing complex assembly. Part of protein-containing complex. Orthologous to human PARD6B (par-6 family cell polarity regulator beta). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Pard6b
Official Name
par-6 family cell polarity regulator beta [Source:RGD Symbol;Acc:1308205]
Ensembl ID
ENSRNOG00000010883
Bio databases IDs NCBI: 362279 Ensembl: ENSRNOG00000010883
Aliases par-6 family cell polarity regulator beta
Synonyms AV025615, PAR6B, par-6 family cell polarity regulator beta, par-6 family cell polarity regulator β
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pard6b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Domain present in PSD-95, Dlg, and ZO-1/2
  • canonical PDZ domain
  • protein binding
  • PDZ binding motif
  • PDZ domain
  • PB1

Pathways

Biological processes and signaling networks where the Pard6b gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
role in cell
  • migration
  • formation
  • formation in
  • development
  • reassembly
  • assembly
  • retention in
  • misorientation in
  • misorientation
  • polarization

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cell junction
  • Cytoplasm
  • apical compartment
  • cell cortex
  • Nucleus
  • cytosol
  • apical cell surfaces
  • membrane ruffles
  • apical membrane
  • tight junctions

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Pard6b gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell division
  • regulation of cellular localization
  • centrosome cycle
  • cell-cell junction assembly
  • macromolecular complex assembly
  • establishment or maintenance of epithelial cell apical/basal polarity
  • axonogenesis
  • establishment or maintenance of cell polarity
  • regulation of cell migration

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • tight junction
  • occluding junction
  • extracellular vesicular exosome
  • cell cortex
  • cytosol
  • plasma membrane
  • apical plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.