Zdhhc13 Gene Summary [Rat]

Predicted to enable magnesium ion transmembrane transporter activity and palmitoyltransferase activity. Predicted to be involved in positive regulation of canonical NF-kappaB signal transduction. Predicted to be located in Golgi membrane; Golgi-associated vesicle membrane; and endoplasmic reticulum. Orthologous to human ZDHHC13 (zinc finger DHHC-type palmitoyltransferase 13). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Zdhhc13
Official Name
zinc finger, DHHC-type containing 13 [Source:RGD Symbol;Acc:1309736]
Ensembl ID
ENSRNOG00000014277
Bio databases IDs NCBI: 365252 Ensembl: ENSRNOG00000014277
Aliases zinc finger, DHHC-type containing 13
Synonyms 2410004E01Rik, C530010M18, DHHC13, HIP14L, HIP3RP, kojak, skc4, zinc finger, DHHC domain containing 13, zinc finger DHHC-type palmitoyltransferase 13
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Zdhhc13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • palmitoyltransferase
  • transcription regulator
  • Ankyrin repeats (many copies)
  • Ankyrin repeats (3 copies)
  • DHHC palmitoyltransferase
  • magnesium ion transporter
  • protein binding
  • Ankyrin repeat
  • ankyrin repeats

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • lung adenocarcinoma
  • lung adenocarcinoma formation
regulated by
regulates
  • cyclic AMP
  • EGFR
  • MC1R
  • magnesium
  • HTT
role in cell
  • palmitoylation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cellular membrane
  • Golgi Apparatus
  • Endoplasmic Reticulum
  • Golgi membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Zdhhc13 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of I-kappaB kinase/NF-kappaB cascade
  • protein palmitoylation

Cellular Component

Where in the cell the gene product is active
  • membrane
  • Golgi-associated vesicle membrane
  • Golgi membrane
  • endoplasmic reticulum

Molecular Function

What the gene product does at the molecular level
  • protein-cysteine S-palmitoleyltransferase activity
  • palmitoyltransferase activity
  • magnesium ion transmembrane transporter activity

Gene-Specific Assays for Results You Can Trust

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