ZDHHC13 Gene Summary [Human]
Predicted to enable magnesium ion transmembrane transporter activity and palmitoyltransferase activity. Involved in positive regulation of I-kappaB kinase/NF-kappaB signaling. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | ZDHHC13 |
| Official Name | zinc finger DHHC-type palmitoyltransferase 13 [Source:HGNC Symbol;Acc:HGNC:18413] |
| Ensembl ID | ENSG00000177054 |
| Bio databases IDs | |
| Aliases | zinc finger DHHC-type palmitoyltransferase 13 |
| Synonyms | 2410004E01Rik, C530010M18, DHHC13, HIP14L, HIP3RP, kojak, skc4, zinc finger, DHHC domain containing 13, zinc finger DHHC-type palmitoyltransferase 13 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZDHHC13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- palmitoyltransferase
- transcription regulator
- Ankyrin repeats (many copies)
- Ankyrin repeats (3 copies)
- DHHC palmitoyltransferase
- magnesium ion transporter
- protein binding
- Ankyrin repeat
- ankyrin repeats
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cellular membrane
- Golgi Apparatus
- Endoplasmic Reticulum
- Golgi membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZDHHC13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of I-kappaB kinase/NF-kappaB cascade
- protein palmitoylation
Cellular Component
Where in the cell the gene product is active
- membrane
- Golgi-associated vesicle membrane
- Golgi membrane
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- protein-cysteine S-palmitoleyltransferase activity
- palmitoyltransferase activity
- magnesium ion transmembrane transporter activity