Syt10 Gene Summary [Rat]

Predicted to enable several functions, including calcium ion sensor activity; phospholipid binding activity; and protein dimerization activity. Predicted to be involved in positive regulation of calcium ion-dependent exocytosis; presynaptic dense core vesicle exocytosis; and sensory perception of smell. Predicted to be located in synaptic vesicle membrane. Predicted to be active in several cellular components, including exocytic vesicle; glutamatergic synapse; and presynapse. Orthologous to human SYT10 (synaptotagmin 10). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Syt10
Official Name
synaptotagmin 10 [Source:RGD Symbol;Acc:62041]
Ensembl ID
ENSRNOG00000014296
Bio databases IDs NCBI: 60567 Ensembl: ENSRNOG00000014296
Aliases synaptotagmin 10
Synonyms SYNAPTOTAGMIN 10, synaptotagmin X
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Syt10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • SNARE binding
  • phospholipid binding
  • binding protein
  • phosphatidylinositol-4,5-bisphosphate binding
  • protein homodimerization
  • calcium ion binding
  • protein binding
  • Protein kinase C conserved region 2 (CalB)
  • identical protein binding
  • protein heterodimerization
  • transporter
  • C2 domain

Pathways

Biological processes and signaling networks where the Syt10 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • diabetic nephropathy
regulated by
  • SYT10
  • NPAS4
  • 2-mercaptoethanol
  • kainic acid
  • MAP3K12
  • (NPAS4:ARNTL,NPAS4:ARNT,NPAS4:ARNT2):SYT10 gene
  • L-norvaline
regulates
role in cell
  • cell death

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • synaptic vesicle membrane
  • glutaminergic synapse
  • exocytic vesicle
  • presynaptic regions
  • vesicles
  • synaptic membrane
  • synaptic vesicles
  • perikaryon

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Syt10 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • sensory perception of smell
  • synaptic transmission
  • calcium ion-dependent exocytosis
  • synaptic vesicle exocytosis
  • positive regulation of calcium ion-dependent exocytosis

Cellular Component

Where in the cell the gene product is active
  • exocytic vesicle
  • transport vesicle membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • phosphatidylinositol-4,5-bisphosphate binding
  • phosphatidylserine binding
  • protein homodimerization activity
  • protein heterodimerization activity
  • calcium ion binding
  • clathrin binding
  • SNARE binding
  • calcium-dependent phospholipid binding

Gene-Specific Assays for Results You Can Trust

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