SYT10 Gene Summary [Human]
Predicted to enable several functions, including phospholipid binding activity; protein dimerization activity; and syntaxin binding activity. Predicted to be involved in several processes, including cellular response to calcium ion; regulation of secretion by cell; and sensory perception of smell. Predicted to be located in synapse and transport vesicle membrane. Predicted to be integral component of membrane. Predicted to be active in exocytic vesicle and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SYT10 |
| Official Name | synaptotagmin 10 [Source:HGNC Symbol;Acc:HGNC:19266] |
| Ensembl ID | ENSG00000110975 |
| Bio databases IDs | |
| Aliases | synaptotagmin 10 |
| Synonyms | SYNAPTOTAGMIN 10, synaptotagmin X |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SYT10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SNARE binding
- phospholipid binding
- binding protein
- phosphatidylinositol-4,5-bisphosphate binding
- protein homodimerization
- calcium ion binding
- protein binding
- Protein kinase C conserved region 2 (CalB)
- identical protein binding
- protein heterodimerization
- transporter
- C2 domain
Pathways
Biological processes and signaling networks where the SYT10 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- synaptic vesicle membrane
- glutaminergic synapse
- exocytic vesicle
- presynaptic regions
- vesicles
- synaptic membrane
- synaptic vesicles
- perikaryon
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SYT10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sensory perception of smell
- synaptic transmission
- calcium ion-dependent exocytosis
- synaptic vesicle exocytosis
- positive regulation of calcium ion-dependent exocytosis
Cellular Component
Where in the cell the gene product is active
- exocytic vesicle
- transport vesicle membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- phosphatidylinositol-4,5-bisphosphate binding
- phosphatidylserine binding
- protein homodimerization activity
- protein heterodimerization activity
- calcium ion binding
- clathrin binding
- SNARE binding
- calcium-dependent phospholipid binding