Syt10 Gene Summary [Mouse]
Enables several functions, including calcium ion binding activity; phospholipid binding activity; and protein dimerization activity. Involved in positive regulation of calcium ion-dependent exocytosis; presynaptic dense core vesicle exocytosis; and sensory perception of smell. Located in exocytic vesicle. Is active in glutamatergic synapse and presynapse. Is expressed in several structures, including alimentary system; brain; cardiovascular system; ear; and skeleton. Orthologous to human SYT10 (synaptotagmin 10). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Syt10 |
| Official Name | synaptotagmin X [Source:MGI Symbol;Acc:MGI:1859546] |
| Ensembl ID | ENSMUSG00000063260 |
| Bio databases IDs | |
| Aliases | synaptotagmin X |
| Synonyms | SYNAPTOTAGMIN 10, synaptotagmin X |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Syt10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SNARE binding
- phospholipid binding
- binding protein
- phosphatidylinositol-4,5-bisphosphate binding
- protein homodimerization
- calcium ion binding
- protein binding
- Protein kinase C conserved region 2 (CalB)
- identical protein binding
- protein heterodimerization
- transporter
- C2 domain
Pathways
Biological processes and signaling networks where the Syt10 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- synaptic vesicle membrane
- glutaminergic synapse
- exocytic vesicle
- presynaptic regions
- vesicles
- synaptic membrane
- synaptic vesicles
- perikaryon
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Syt10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sensory perception of smell
- synaptic transmission
- calcium ion-dependent exocytosis
- synaptic vesicle exocytosis
- positive regulation of calcium ion-dependent exocytosis
Cellular Component
Where in the cell the gene product is active
- exocytic vesicle
- transport vesicle membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- phosphatidylinositol-4,5-bisphosphate binding
- phosphatidylserine binding
- protein homodimerization activity
- protein heterodimerization activity
- calcium ion binding
- clathrin binding
- SNARE binding
- calcium-dependent phospholipid binding