Qsox2 Gene Summary [Rat]
Predicted to enable flavin-dependent sulfhydryl oxidase activity and protein disulfide isomerase activity. Predicted to be involved in protein folding. Predicted to be located in Golgi apparatus and nucleoplasm. Predicted to be active in Golgi membrane and extracellular space. Orthologous to human QSOX2 (quiescin sulfhydryl oxidase 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Qsox2 |
| Official Name | quiescin sulfhydryl oxidase 2 [Source:RGD Symbol;Acc:1584720] |
| Ensembl ID | ENSRNOG00000018574 |
| Bio databases IDs | |
| Aliases | quiescin sulfhydryl oxidase 2 |
| Synonyms | BC030934, LOC103691753, LOC687383, QSCN6L1, quiescin Q6 sulfhydryl oxidase 2, quiescin Q6 sulphydryl oxidase 2, quiescin sulfhydryl oxidase 2, quiescin sulphydryl oxidase 2, SOXN |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Qsox2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- QSOX Trx-like domain
- Erv1 / Alr family
- Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
- Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase
- enzyme
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Golgi Apparatus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Qsox2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein folding
Cellular Component
Where in the cell the gene product is active
- nuclear membrane
- extracellular space
- Golgi apparatus
- Golgi membrane
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein disulfide isomerase activity
- flavin-linked sulfhydryl oxidase activity