Qsox2 Gene Summary [Mouse]

This gene encodes a member of the sulfhydryl oxidase protein family. Members of this family catalyze formation of disulfide bonds. A similar protein in humans may sensitize neuroblastoma cells to interferon gamma-induced cell death. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Details

Type
Protein Coding
Official Symbol
Qsox2
Official Name
quiescin Q6 sulfhydryl oxidase 2 [Source:MGI Symbol;Acc:MGI:2387194]
Ensembl ID
ENSMUSG00000036327
Bio databases IDs NCBI: 227638 Ensembl: ENSMUSG00000036327
Aliases quiescin Q6 sulfhydryl oxidase 2
Synonyms BC030934, LOC103691753, LOC687383, QSCN6L1, quiescin Q6 sulfhydryl oxidase 2, quiescin Q6 sulphydryl oxidase 2, quiescin sulfhydryl oxidase 2, quiescin sulphydryl oxidase 2, SOXN
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Qsox2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • QSOX Trx-like domain
  • Erv1 / Alr family
  • Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
  • Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase
  • enzyme

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • insomnia
  • refractive error
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Golgi Apparatus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Qsox2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein folding

Cellular Component

Where in the cell the gene product is active
  • nuclear membrane
  • extracellular space
  • Golgi apparatus
  • Golgi membrane
  • plasma membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein disulfide isomerase activity
  • flavin-linked sulfhydryl oxidase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.