Gfra4

Enables glial cell-derived neurotrophic factor receptor activity. Predicted to be involved in glial cell-derived neurotrophic factor receptor signaling pathway and nervous system development. Predicted to act upstream of or within negative regulation of ossification. Located in extracellular space. Orthologous to human GFRA4 (GDNF family receptor alpha 4). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gfra4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Gfra4 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Gfra4 gene, providing context for its role in the cell.