Col6a6 Gene Summary [Rat]

Predicted to be involved in extracellular matrix organization. Predicted to be located in extracellular matrix and extracellular region. Predicted to be active in collagen-containing extracellular matrix. Orthologous to human COL6A6 (collagen type VI alpha 6 chain). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Col6a6
Official Name
collagen type VI alpha 6 chain [Source:RGD Symbol;Acc:1309172]
Ensembl ID
ENSRNOG00000023007
Bio databases IDs NCBI: 315979 Ensembl: ENSRNOG00000023007
Aliases collagen type VI alpha 6 chain
Synonyms collagen, type VI, alpha 6, collagen type VI alpha 6 chain, collagen, type VI, α 6, collagen type VI α 6 chain, E330019B14, E330026B02Rik, LOC686258, LOC686266, RGD1309172
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Col6a6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • von Willebrand factor (vWF) type A domain
  • vWFA
  • Collagen triple helix repeat (20 copies)
  • von Willebrand factor type A domain

Pathways

Biological processes and signaling networks where the Col6a6 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Ullrich congenital muscular dystrophy
  • insulin resistance
  • rotator cuff injury
  • glomerulonephritis
  • aortic valve calcification
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • extracellular matrix

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Col6a6 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell adhesion

Cellular Component

Where in the cell the gene product is active
  • collagen
  • extracellular matrix
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • extracellular matrix structural constituent conferring tensile strength

Gene-Specific Assays for Results You Can Trust

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