Stk40 Gene Summary [Rat]
Predicted to enable ATP binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Predicted to be involved in regulation of MAPK cascade. Predicted to act upstream of or within several processes, including glycogen metabolic process; lung development; and respiratory system process. Predicted to be located in cytosol and nucleoplasm. Orthologous to human STK40 (serine/threonine kinase 40). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Stk40 |
| Official Name | serine/threonine kinase 40 [Source:RGD Symbol;Acc:727884] |
| Ensembl ID | ENSRNOG00000025679 |
| Bio databases IDs | |
| Aliases | serine/threonine kinase 40 |
| Synonyms | 2310004N11Rik, Lyk4, RGD1307310, serine/threonine kinase 40, SgK495, SHIK |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Stk40 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- Serine/Threonine protein kinases, catalytic domain
- protein serine/threonine kinase
- Protein Kinases, catalytic domain
- protein binding
- Protein kinase domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- atelectasis
- respiratory distress
role in cell
- production in
- phosphorylation in
- apoptosis
- expression in
- differentiation
- activation in
- number
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Stk40 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- multicellular organism growth
- respiratory system process
- lung alveolus development
- regulation of MAPK cascade
- glycogen metabolic process
- negative regulation of apoptotic process
- regulation of gene expression
- lung morphogenesis
Cellular Component
Where in the cell the gene product is active
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein binding
- protein serine/threonine kinase activity