Dynlrb1 Gene Summary [Rat]
Predicted to enable dynein intermediate chain binding activity and identical protein binding activity. Involved in visual behavior. Located in cytoplasm. Orthologous to human DYNLRB1 (dynein light chain roadblock-type 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dynlrb1 |
| Official Name | dynein light chain roadblock-type 1 [Source:RGD Symbol;Acc:619910] |
| Ensembl ID | ENSRNOG00000025715 |
| Bio databases IDs | |
| Aliases | dynein light chain roadblock-type 1 |
| Synonyms | 2010012N15Rik, 2010320M17Rik, 9430076K19RIK, AV124457, BITH, BLP, DNCL2A, DNLC2A, dynein light chain roadblock-type 1, KM23, km23-1, RKM23, ROADBLOCK-1, ROBLD1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Dynlrb1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Roadblock/LC7 domain
- identical protein binding
Pathways
Biological processes and signaling networks where the Dynlrb1 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- ovarian endometrioid carcinoma
- endometrioid ovarian cancer
- cystadenocarcinoma
- metastatic ovarian cancer
regulates
- SERPINE1
- Mix.2
role in cell
- misalignment in
- misalignment
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ciliary tip
- cilia
- centrosome
- growth cone
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Dynlrb1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- microtubule-based movement
- visual behavior
Cellular Component
Where in the cell the gene product is active
- centrosome
- cytoplasmic dynein complex
- cytoplasm
- membrane
- dynein complex
- cilium
- microtubule
Molecular Function
What the gene product does at the molecular level
- microtubule motor activity
- protein binding
- dynein intermediate chain binding